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ea0019p106 | Clinical practice/governance and case reports | SFEBES2009

The challenges of implementing consensus recommendations for GH therapy in GHD adolescent survivors of childhood cancer during the transition period

Gleeson H , Whitehouse A , Smethurst L , Shalet S , Brennan B , Clayton P

Background: Re-evaluation of the diagnosis of GHD at the completion of linear growth is a key task.Objectives: To audit the impact of consensus recommendations on diagnosis of GHD and initiation of GH therapy in adolescents previously treated for a brain tumour (BT) or haematological malignancy (HM).Population: Sixty one patients who had received GH therapy until final height following treatment for a BT (n=40) or a HM (n...

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ea0011p607 | Neuroendocrinology and behaviour | ECE2006

Hypothalamic-pituitary dysfunction following irradiation of non-pituitary brain tumours in adults

Agha A , Sherlock M , Brennan S , O’Connor SA , O’Sullivan E , Rogers B , Faul C , Rawluk D , Tormey W , Thompson C.J.

Hypothalamic-pituitary (HP) dysfunction is common in children treated with cranial radiotherapy (RT) for brain tumours but there is little known about the risk of HP dysfunction in adults treated with RT for primary non-pituitary brain tumours.We aimed to investigate the frequency of HP dysfunction in adults after RT for primary brain tumours which are distant from the HP region.We studied 56 adult patients who received external be...

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Endocrine Abstracts

The challenges of implementing consensus recommendations for GH therapy in GHD adolescent survivors of childhood cancer during the transition period

Hypothalamic-pituitary dysfunction following irradiation of non-pituitary brain tumours in adults

BiosciAbstracts